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Dr Nick Wong will present on 'NGS at scale : Considerations when designing a High Throughput Genomic Assay for the ASPREE Study.'

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About MPCCC Tech Talks

MPCCC Tech Talks aim to engage the MPCCC clinical and research communities to share expertise and knowledge about state-of-the-art technological innovations in cancer medicine. A ‘bench to bedside’ translational approach is fundamental to research at MPCCC partners, and these talks are a platform for sharing information and discussion, to enhance research capabilities in our workforce, encourage multi-disciplinary interaction and establish a supportive community.

NGS at scale : Considerations when designing a High Throughput Genomic Assay for the ASPREE Study

Clonal Haematopoiesis of Indeterminate Potential (CHIP) is development of detectable clones with somatic mutations associated with leukaemogenesis in otherwise normal, healthy people, and has been associated with increased risk of cardiovascular disease as well as blood cancers.

The The ASPREE (ASPirin in Reducing Events in the Elderly) trial on patients with CHIP will be used as a case study to explore commonly held beliefs about high throughput genomics in this talk. Nick will use the ASPREE-CHIP project as a working example of exploiting the power of automation, but also highlight the potential pitfalls too.

About the speaker: Dr Nick Wong

Nick is a member of the Monash Bioinformatics Platform and based at the Central Clinical School, The Alfred Hospital. He obtained his PhD in 2006 under Prof K. H. Andy Choo, University of Melbourne looking at the epigenetics of neocentromeres. Nick continued on to study the extent of DNA methylation markers in a range of cancers including paediatric ALL before moving to an industry R and D role at Pacific Edge, in Dunedin NZ, looking at bladder cancer biomarkers. Nick formally trained in molecular biology and has a keen interest in genomic technologies.

Event details

Friday 30 October, 2-3pm, online via Zoom.

Registration details will be circulated 1 hour prior to event commencement.

Please note this event will be recorded and published on the MPCCC website.

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