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Distinguished Seminar - Ruirui Qiao - Monash University
Date and time
Location
Lecture Theatre S10
16 Rainforest Walk Clayton Campus, VIC 3800 AustraliaDescription
Polymer grafted inorganic nanoparticles towards in vivo molecule imaging applications
Rurui Qiao
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia
*Email: Ruirui.qiao@monash.edu
Owing to the excellent imaging performance and versatility of multimodal, stimuli-responsive, and targeted imaging, inorganic nanoparticle-based nanoparticles have been extensively investigated as a potential alternative to conventional molecular imaging probes. 1-2 The current talk will mainly focus on the development of advanced molecular imaging probes based on the polymer grafted inorganic nanoparticles.3-5 In vivo imaging applications in MRI, optical, and dual-modality imaging using nanoprobes which can act as a diagnostic and prognostic marker for a variety of morbidities (e.g. tumour, cardiovascular disease) will be intensively discussed.3, 6-7
References
1. Qiao, R.; Yang, C.; Gao, M., Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications, J Mater Chem, 2009, 19 (35), 6274-6293.
2. Qiao, R.; Zeng, J. F.; Jia, Q. J.; Du, J.; Shen, L.; Gao, M. Y., Magnetic Iron Oxide Nanoparticle—an Important Cornerstone of MR Molecular Imaging of Tumors, Acta Physico - Chimica Sinica 2012, 28 (5), 993-1011.
3. Hou, Y.; Qiao, R.; Fang, F.; Wang, X.; Dong, C.; Liu, K; Liu, C; Liu, Z.; Lei, H.; Wang, F.; Gao, M., NaGdF4 nanoparticle-based molecular probes for magnetic resonance imaging of intraperitoneal tumor xenografts in vivo, ACS Nano 7(1) (2013) 330-338.
4. Tang, S. Y.; Qiao, R.; Yan, S.; Yuan, D.; Zhao, Q. B.; Yun, G. L.; Davis, T. P.; Li, W. H., Microfluidic Mass Production of Stabilized and Stealthy Liquid Metal Nanoparticles. Small 2018, 14 (21), 1800118.
5. Qiao, R.; Esser, L.; Fu, C.; Zhang, C.; Hu, J.; Ramírez-arcía, P.; Li, Y.; Quinn, J. F.; Whittaker, M. R.; Whittaker, A. K.; Davis, T. P., Bioconjugation and Fluorescence Labeling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-Terminal Polymers. Biomacromolecules 2018, 19, 4423-4429.
6. Qiao, R.; Liu, C.; Liu, M.; Hu, H.; Liu, C.; Hou, Y.; Wu, K.; Lin, Y.; Liang, J.; Gao, M., Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles, ACS Nano, 9 (2), 2120-2129.
7. Qiao, R.; Qiao, H.; Zhang Y.; Chi C.; Tian J.; Zhang L.; Cao F.; Gao M.; Molecular Imaging of Vulnerable Atherosclerotic Plaques in Vivo with Osteopontin-Specific Upconversion Nanoprobes, ACS Nano, 2017, 11 (2), 1816-1825.
Ruirui Qiao
Title: Research Fellow
1ARC Centre of Excellence in Convergent Bio-Nano Science and Technology,
Monash Institute of Pharmaceutical Sciences, Monash University, Parkville,
VIC 3052, Australia
Dr. Ruirui Qiao is a research fellow in Monash Institute of Pharmaceutical Sciences. Before she was an assciociate Prof in Institute of Chemistry, Chinese Academy of Sciences (ICCAS). She obtianed her Ph.D. in ICCAS of Sciences in 2014. She published >40 peer-review scientific papers, with citation by >2500 times (H-index~25). She was awarded a Research Stays for University Academics and Scientists Scholarship from DAAD (Germany) in 2015, and was invited as a visiting professor by three different groups at the University of Muenster, University of Munich (LMU), and University Medical Centre Mainz. She is also an Awardee of the frist prize of science and technology of Beijng (4/5).
Biography
Dr. Qiao received her Bachelor and Master’s degree in Pharmaceutical Science from Peking University and obtained her PhD degree in Physical Chemistry from Chinese Academy of Science in 2014. She worked as a research assistant (2007-2009) and Associate Research Fellow (2009-2016) at the Institute of Chemistry, Chinese Academy of Sciences (ICCAS) in Prof Mingyuan Gao’s group. In 2016, she was promoted to be an associate Professor and project leader at the CAS Key laboratory of colloidal, interface and chemical thermodynamics in ICCAS. In 2017, she joined Prof Thomas Davis’ group in Monash Institute of Pharmaceutical Sciences (MIPS) as a research fellow and co-leader of signature project in ARC Centre of Excellence in Convergent Bio-Nano Science & Technology (CBNS). She has authored/co-authored over 50 peer-reviewed papers and 2 book chapters with >2800 citations. Her current research is focusing on multifunctional inorganic/organic nanohybrids for molecular imaging and drug delivery applications.